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inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKK-epsilon)

Target Class
Kinase
Family
Other
Official Symbol
IKBKE
Entrez Gene ID
9641
Species
Human
Accession Number
NP_054721.1
Alias Names
I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IKK-i; IKK-related kinase epsilon; IKKE; IKKI; inducible I kappa-B kinase; inducible IkappaB kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon
Background
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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