Targets / Kinase / ICK

intestinal cell (MAK-like) kinase (ICK)

Target Class
Kinase
Family
CMGC
Official Symbol
ICK
Entrez Gene ID
22858
Species
Human
Accession Number
NP_055735.1
Alias Names
ECO; LCK2; MAK-related kinase; MRK; hICK; intestinal cell (MAK-like) kinase; laryngeal cancer kinase 2; serine/threonine protein kinase; serine/threonine-protein kinase ICK
Background
Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]
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Related Group Members: CMGC
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