Targets / Kinase / GSK3B

glycogen synthase kinase 3 beta (GSK3B)

Target Class
Kinase
Family
CMGC
Official Symbol
GSK3B
Entrez Gene ID
2932
Species
Human
Accession Number
NP_002084.2
Alias Names
GSK-3 beta; GSK3beta isoform; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 beta; serine/threonine-protein kinase GSK3B
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
+ Show More

Solution Portfolio

Related Group Members: CMGC
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


LeadHunter Screening & Profiling Services
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available