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G protein-coupled receptor kinase 1 (GRK1)

Target Class
Kinase
Family
AGC
Official Symbol
GRK1
Entrez Gene ID
6011
Species
Human
Accession Number
NP_002920.1
Alias Names
G protein-coupled receptor kinase 1; GPRK1; RHOK; RK; rhodopsin kinase
Background
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Group Members: AGC
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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