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fms-related tyrosine kinase 4 (FLT4)

Target Class
Kinase
Family
Receptor Tyrosine Kinase
Official Symbol
FLT4
Species
Human
Accession Number
NM_182925
Alias Names
FLT-4; FLT41; LMPH1A; PCL; VEGFR-3; VEGFR3; fms-like tyrosine kinase 4; fms-related tyrosine kinase 4; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; tyrosine-protein kinase receptor FLT4; vascular endothelial growth factor receptor 3
Background
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Group Members: Receptor Tyrosine Kinase
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Measures Background Species Cell Line
Receptor Phosphorylation U2OS Human 93-0888C3
Assay Measures Background Species Assay Kit
Receptor Phosphorylation U2OS Human 93-0888E3CP16S
Receptor Phosphorylation U2OS Human 93-0888E3CP16M
Receptor Phosphorylation U2OS Human 93-0888E3CP16L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available Available