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mitogen-activated protein kinase 6 (ERK3)

Target Class
Kinase
Family
CMGC
Official Symbol
MAPK6
Entrez Gene ID
5597
Species
Human
Accession Number
NP_002739.1
Alias Names
ERK-3; ERK3; HsT17250; MAP kinase 6; MAP kinase isoform p97; MAPK 6; PRKM6; extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; mitogen-activated protein kinase 6; p97-MAPK; p97MAPK; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6
Background
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008]
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Related Group Members: CMGC
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