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Ephrin type-A receptor 5 (EphA5)

Target Class
Kinase
Family
Receptor Tyrosine Kinase
Official Symbol
EphA5
Species
Human
Accession Number
NM_004439
Alias Names
CEK7; EHK-1; EHK1; EK7; EPH homology kinase 1; EPH receptor A5; EPH-like kinase 7; Eph homology kinase-1; EphA5; HEK7; TYRO4; brain-specific kinase; ephrin type-A receptor 5; receptor protein-tyrosine kinase HEK7; tyrosine-protein kinase receptor EHK-1
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]
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Solution Portfolio

Related Group Members: Receptor Tyrosine Kinase
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Measures Background Species Cell Line
Receptor Phosphorylation U2OS Human 93-0840C3
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available Available