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casein kinase 2, alpha 1 polypeptide (CSNK2A1)

Target Class
Kinase
Family
Other
Official Symbol
CSNK2A1
Entrez Gene ID
1457
Species
Human
Accession Number
NP_001886.1
Alias Names
CK II alpha; CK2 catalytic subunit alpha; CK2A1; CKII; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 subunit; casein kinase II subunit alpha; protein kinase CK2
Background
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
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