Targets / Kinase / AURKA

aurora kinase A (AURKA)

Target Class
Kinase
Family
Other
Official Symbol
AURKA
Entrez Gene ID
6790
Species
Human
Accession Number
NP_003591.2
Alias Names
serine/threonine kinase 6; AIK; ARK-1; ARK1; AURA; AURORA2; BTAK; IPL1-related kinase; PPP1R47; STK15; STK6; STK7; aurora 2; aurora kinase A; aurora-related kinase 1; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; breast tumor-amplified kinase; breast-tumor-amplified kinase; hARK1; protein phosphatase 1, regulatory subunit 47; serine/threonine kinase 15; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine-protein kinase 15; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-A
Background
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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