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ankyrin repeat and kinase domain containing 1 (ANKK1)

Target Class
Kinase
Family
TKL
Official Symbol
ANKK1
Entrez Gene ID
255239
Species
Human
Accession Number
NP_848605.1
Alias Names
PKK2; X-kinase; ankyrin repeat and kinase domain containing 1; ankyrin repeat and protein kinase domain-containing protein 1; protein kinase PKK2; sgK288; sugen kinase 288
Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]
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Related Group Members: TKL
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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