Find a Product

protein kinase, AMP-activated, alpha 2 catalytic subunit (AMPK-alpha1)

Target Class
Official Symbol
Entrez Gene ID
Accession Number
Alias Names
5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK alpha 1; AMPK subunit alpha-1; AMPKa1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
+ Show More

Solution Portfolio

Related Group Members: CAMK

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan