Targets / Kinase / ACVR1B
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activin A receptor, type IB (ACVR1B)

Target Class
Kinase
Family
TKL
Official Symbol
ACVR1B
Entrez Gene ID
91
Species
Human
Accession Number
NP_004293.1
Alias Names
ACTRIB; ACVRLK4; ALK4; SKR2; activin A receptor, type IB; activin A receptor, type II-like kinase 4; activin receptor type-1B; activin receptor-like kinase 4; serine/threonine-protein kinase receptor R2
Background
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
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Solution Portfolio

Related Group Members: TKL
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Cell Lines
Assay Measures Background Species Cell Line
ACVR1B/BMPR2 Dimerization U2OS Human 93-1072C3
Ready to Use eXpress Kits
Assay Measures Background Species Assay Kit
ACVR1B/BMPR2 Dimerization U2OS Human 93-1072E3CP5M
ACVR1B/BMPR2 Dimerization U2OS Human 93-1072E3CP5L
LeadHunter Screening & Profiling Services
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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