Thyrotropin-releasing hormone receptor (TRH1)
- Target Class
- GPCR
- Family
- Thyrotropin releasing hormone
- Official Symbol
- TRHR
- Species
- Human
- Accession Number
- AY493373
- Alias Names
- TRH-R; thyroliberin receptor; thyrotropin-releasing hormone receptor
- Background
This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]
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Solution Portfolio
Related Family Members:
Thyrotropin releasing hormone
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0239C2 |
| Internalization |
U2OS |
Human |
93-0949C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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