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Somatostatin receptor 5 (SST5)

Target Class
GPCR
Family
Somatostatin
Official Symbol
SSTR5
Species
Human
Accession Number
NM_001053
Alias Names
SS-5-R; somatostatin receptor 5; somatostatin receptor subtype 5; somatostatin receptor type 5
Background
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]
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Solution Portfolio

Related Family Members:

Somatostatin
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0402C2
β-Arrestin U2OS Human 93-0402C3
cAMP CHO-K1 Human 95-0133C2
Assay Readout Background Species Assay Kit
β-Arrestin U2OS Human 93-0402E3CP0S
β-Arrestin U2OS Human 93-0402E3CP0M
β-Arrestin U2OS Human 93-0402E3CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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