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Prostaglandin I2 (prostacyclin) receptor (IP) (IP1)

Target Class
GPCR
Family
Prostanoid
Official Symbol
PTGIR
Species
Human
Accession Number
AY242134
Alias Names
IP; PGI receptor; PGI2 receptor; PRIPR; prostacyclin receptor; prostaglandin I2 (prostacyclin) receptor (IP); prostaglandin I2 receptor; prostanoid IP receptor
Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Prostanoid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
cAMPCHO-K1Human95-0051C2
InternalizationU2OSHuman93-0838C3
β-ArrestinHEK 293Human93-0305C1
β-ArrestinCHO-K1Human93-0305C2
 
Assay Readout ▲BackgroundSpeciesAssay Kit
cAMPCHO-K1Human95-0051E2CP2S
cAMPCHO-K1Human95-0051E2CP2M
cAMPCHO-K1Human95-0051E2CP2L
InternalizationU2OSHuman93-0838E3CP0S
InternalizationU2OSHuman93-0838E3CP0M
InternalizationU2OSHuman93-0838E3CP0L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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