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Prostaglandin I2 (prostacyclin) receptor (IP) (IP1)

Target Class
GPCR
Family
Prostanoid
Official Symbol
PTGIR
Species
Human
Accession Number
AY242134
Alias Names
IP; PGI receptor; PGI2 receptor; PRIPR; prostacyclin receptor; prostaglandin I2 (prostacyclin) receptor (IP); prostaglandin I2 receptor; prostanoid IP receptor
Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Prostanoid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin HEK 293 Human 93-0305C1
β-Arrestin CHO-K1 Human 93-0305C2
Internalization U2OS Human 93-0838C3
cAMP CHO-K1 Human 95-0051C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0051E2CP2S
cAMP CHO-K1 Human 95-0051E2CP2M
cAMP CHO-K1 Human 95-0051E2CP2L
Internalization U2OS Human 93-0838E3CP0S
Internalization U2OS Human 93-0838E3CP0M
Internalization U2OS Human 93-0838E3CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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