Prostaglandin D2 receptor (DP1)
- Target Class
- GPCR
- Family
- Prostanoid
- Official Symbol
- PTGDR
- Species
- Human
- Accession Number
- NM_000953
- Alias Names
- AS1; ASRT1; DP; DP1; PGD receptor; PGD2 receptor; PTGDR1; prostaglandin D2 receptor; prostaglandin D2 receptor (DP)
- Background
The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Prostanoid
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| cAMP |
CHO-K1 |
Human |
95-0110C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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