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Prostaglandin D2 receptor (DP1)

Target Class
GPCR
Family
Prostanoid
Official Symbol
PTGDR
Species
Human
Accession Number
NM_000953
Alias Names
AS1; ASRT1; DP; DP1; PGD receptor; PGD2 receptor; PTGDR1; prostaglandin D2 receptor; prostaglandin D2 receptor (DP)
Background
The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Prostanoid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0110C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0110E2CP2S
cAMP CHO-K1 Human 95-0110E2CP2M
cAMP CHO-K1 Human 95-0110E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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