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Purinergic receptor P2Y, G-protein coupled, 12 (P2Y12)

Target Class
GPCR
Family
P2Y
Official Symbol
P2RY12
Species
Human
Accession Number
AY136754
Alias Names
ADP-glucose receptor; ADPG-R; BDPLT8; G-protein coupled receptor SP1999; Gi-coupled ADP receptor HORK3; HORK3; P2T(AC); P2Y purinoceptor 12; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; P2Y12 platelet ADP receptor; SP1999; purinergic receptor P2RY12; purinergic receptor P2Y, G-protein coupled, 12; putative G-protein coupled receptor
Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

P2Y
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
InternalizationU2OSHuman93-0952C3
β-ArrestinCHO-K1Human93-0262C2
 
Assay Readout ▲BackgroundSpeciesAssay Kit
β-ArrestinCHO-K1Human93-0262E2CP0S
β-ArrestinCHO-K1Human93-0262E2CP0M
β-ArrestinCHO-K1Human93-0262E2CP0L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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