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Purinergic receptor P2Y, G-protein coupled, 1 (P2RY1)

Target Class
GPCR
Family
P2Y
Official Symbol
P2RY1
Species
Human
Accession Number
NM_002563.2
Alias Names
ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; P2Y1; platelet ADP receptor; purinergic receptor P2Y, G-protein coupled, 1
Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

P2Y
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
Calcium 1321N1 Human 95-1018C6
β-Arrestin U2OS Human 93-0941C3
Internalization U2OS Human 93-0967C3
Assay Readout Background Species Assay Kit
β-Arrestin U2OS Human 93-0941E3CP5S
β-Arrestin U2OS Human 93-0941E3CP5M
β-Arrestin U2OS Human 93-0941E3CP5L
Internalization U2OS Human 93-0967E3CP0S
Internalization U2OS Human 93-0967E3CP0M
Internalization U2OS Human 93-0967E3CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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