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Opioid receptor-like receptor (NOP)

Target Class
GPCR
Family
Opioid
Official Symbol
OPRL1
Species
Human
Accession Number
AY268428
Alias Names
KOR-3; NOCIR; OOR; ORL1; kappa-type 3 opioid receptor; kappa3-related opioid receptor; nociceptin receptor; opiate receptor-like 1; orphanin FQ receptor
Background
The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2011]
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Solution Portfolio

Related Family Members:

Opioid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0264C2
cAMP CHO-K1 Human 95-0115C2
Internalization U2OS Human 93-0904C3
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0115E2CP2S
cAMP CHO-K1 Human 95-0115E2CP2M
cAMP CHO-K1 Human 95-0115E2CP2L
β-Arrestin CHO-K1 Human 93-0264E2CP0S
β-Arrestin CHO-K1 Human 93-0264E2CP0M
β-Arrestin CHO-K1 Human 93-0264E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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