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Opioid receptor kappa (κ)

Target Class
GPCR
Family
Opioid
Official Symbol
OPRK1
Species
Human
Accession Number
AF498922
Alias Names
K-OR-1; KOR; KOR-1; OPRK; Opiate receptor, kappa-1; kappa opioid receptor; kappa-type opioid receptor; opioid receptor, kappa 1
Background
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
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Solution Portfolio

Related Family Members:

Opioid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin U2OS Human 93-0234C3
Internalization U2OS Human 93-0828C3
cAMP CHO-K1 Human 95-0088C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0088E2CP2S
cAMP CHO-K1 Human 95-0088E2CP2M
cAMP CHO-K1 Human 95-0088E2CP2L
β-Arrestin U2OS Human 93-0234E3CP5S
β-Arrestin U2OS Human 93-0234E3CP5M
β-Arrestin U2OS Human 93-0234E3CP5L
Internalization U2OS Human 93-0828E3CP0S
Internalization U2OS Human 93-0828E3CP0M
Internalization U2OS Human 93-0828E3CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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