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Neuropeptide FF receptor 1 (NPFF1)

Target Class
GPCR
Family
Neuropeptide FF & AF
Official Symbol
NPFFR1
Species
Human
Accession Number
NM_022146
Alias Names
G protein-coupled receptor 147; G-protein coupled receptor 147; GPR147; NPFF1; NPFF1R1; OT7T022; RFamide-related peptide receptor OT7T022; neuropeptide FF 1; neuropeptide FF receptor 1
Background
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
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Solution Portfolio

Related Family Members:

Neuropeptide FF & AF
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0097C2
β-Arrestin CHO-K1 Human 93-0944C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0097E2CP2S
cAMP CHO-K1 Human 95-0097E2CP2M
cAMP CHO-K1 Human 95-0097E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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