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Chemokine (C-X-C motif) receptor 2 (mCXCR2)

Target Class
GPCR
Family
Chemokine
Official Symbol
mCXCR2
Species
Mouse
Accession Number
NM_009909
Alias Names
C-X-C chemokine receptor type 2; CD128; CDw128; CXC-R2; CXCR-2; Cmkar2; GRO/MGSA receptor; Gpcr16; IL-8 receptor alpha chain; IL-8R B; IL-8Rh; IL-8rb; IL8RA; Il8rb; chemokine (C-X-C motif) receptor 2; chemokine (C-X-C) receptor 2; high affinity interleukin-8 receptor B; interleukin 8 receptor, beta; interleukin-8 receptor type B; mIL-8RH
Background
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
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Solution Portfolio

Related Family Members:

Chemokine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Mouse 93-0513C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Mouse 93-0513E2MCP0S
β-Arrestin CHO-K1 Mouse 93-0513E2MCP0M
β-Arrestin CHO-K1 Mouse 93-0513E2MCP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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