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Chemokine (C-C motif) receptor 4 (mCCR4)

Target Class
GPCR
Family
Chemokine
Official Symbol
mCCR4
Species
Mouse
Accession Number
NM_009916.2
Alias Names
C-C CKR-4; C-C chemokine receptor type 4; CC CKR-4; CC-CKR-4; CCR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; fusin; leukocyte-expressed seven-transmembrane-domain receptor
Background
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol- calcium second messenger system. Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock. In the CNS, could mediate hippocampal-neuron survival.
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Solution Portfolio

Related Family Members:

Chemokine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesAssay Kit
β-ArrestinCHO-K1Mouse93-0515E2MCP0S
β-ArrestinCHO-K1Mouse93-0515E2MCP0M
β-ArrestinCHO-K1Mouse93-0515E2MCP0L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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