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Chemokine (C-C motif) receptor 4 (mCCR4)

Target Class
GPCR
Family
Chemokine
Official Symbol
mCCR4
Species
Mouse
Accession Number
NM_009916.2
Alias Names
C-C CKR-4; C-C chemokine receptor type 4; CC CKR-4; CC-CKR-4; CCR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; fusin; leukocyte-expressed seven-transmembrane-domain receptor
Background
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol- calcium second messenger system. Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock. In the CNS, could mediate hippocampal-neuron survival.
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Solution Portfolio

Related Family Members:

Chemokine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Mouse 93-0515C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Mouse 93-0515E2MCP0S
β-Arrestin CHO-K1 Mouse 93-0515E2MCP0M
β-Arrestin CHO-K1 Mouse 93-0515E2MCP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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