Chemokine (C-C motif) receptor 4 (mCCR4)
- Target Class
- GPCR
- Family
- Chemokine
- Official Symbol
- mCCR4
- Species
- Mouse
- Accession Number
- NM_009916.2
- Alias Names
- C-C CKR-4; C-C chemokine receptor type 4; CC CKR-4; CC-CKR-4; CCR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; fusin; leukocyte-expressed seven-transmembrane-domain receptor
- Background
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol- calcium second messenger system. Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock. In the CNS, could mediate hippocampal-neuron survival.
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Solution Portfolio
Related Family Members:
Chemokine
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Mouse |
93-0515C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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