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Melanocortin receptor 3 (MC3)

Target Class
GPCR
Family
Melanocortin
Official Symbol
MC3R
Species
Human
Accession Number
AY227893
Alias Names
BMIQ9; MC3; MC3-R; OB20; OQTL; Obesity quantitative trait locus; melanocortin 3 receptor; melanocortin receptor 3
Background
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Melanocortin
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
Internalization U2OS Human 93-0837C3
cAMP CHO-K1 Human 95-0045C2
β-Arrestin U2OS Human 93-0984C3
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0045E2CP2S
cAMP CHO-K1 Human 95-0045E2CP2M
cAMP CHO-K1 Human 95-0045E2CP2L
Internalization U2OS Human 93-0837E3CP0S
Internalization U2OS Human 93-0837E3CP0M
Internalization U2OS Human 93-0837E3CP0L
β-Arrestin U2OS Human 93-0984E3CP5S
β-Arrestin U2OS Human 93-0984E3CP5M
β-Arrestin U2OS Human 93-0984E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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