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Adenylate Cyclase Activating Polypeptide 1 Receptor 1 (mPAC1)

Target Class
GPCR
Family
VIP and PACAP
Official Symbol
mADCYAP1R1
Species
Mouse
Accession Number
NM_001025372.1
Alias Names
2900024I10Rik; AI846590; PAC1; PAC1R; PACAP type I receptor; PACAP-R-1; PACAP-R1; PACAP1-R; adenylate cyclase activating polypeptide 1 receptor 1; pituitary adenylate cyclase-activating polypeptide type I receptor
Background
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
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Solution Portfolio

Related Family Members:

VIP and PACAP
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Arrestin Assays
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DiscoveRx PathHunter ß-Arrestin GPCR assays are a cell-based functional assay that quantitatively measures GPCR activation through ß-Arrestin recruitment to activated GPCRs. This offers a simple, yet powerful screening and profiling platform that can be used for almost all Gi-, Gs-, or Gq-coupled receptor. Learn more about our Arrestin Assays.

Assay Readout Background Cell Lines
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DiscoveRx offers stable and validated cell lines of unsurpassed quality and leading performance, engineered using our proprietary EFC technology. These engineered cell lines form the basis of our cell-based assays for a broad range of target classes in a variety of cell backgrounds, ideal for screening and profiling both small molecules and biologics. Learn more about our Cell Lines.

Assay Ready Kits
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DiscoveRx Assay Ready kits are ready-to-ship, ready-to-use kits that contain all the necessary reagents to perform a functional whole-cell assay including frozen pre-validated cells, detection reagents, media and plates, with a simple thaw-plate-read protocol. DiscoveRx offers a variety of Assay Ready kits. Learn more about our Assay Ready Kits.

Orthologs Services
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DiscoveRx offers a variety of service options designed to support you at every stage of drug development. We offer screening and profiling services for small molecules and biologics, using DiscoveRx cell lines anchored in the EFC and competition binding technology platforms. We can develop custom assay solutions tailored to meet your needs and provide scale up options for our cell lines and supporting components. Learn more about DiscoveRx Services.

β-Arrestin-2 CHO-K1 93-0594C2 eXpress
Yes
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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