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Choriogonadotropin receptor (LH)

Target Class
GPCR
Family
Glycoprotein hormone receptor
Official Symbol
LHCGR
Species
Human
Accession Number
NM_000233
Alias Names
HHG; LCGR; LGR2; LH/CG-R; LH/CGR; LHR; LHRHR; LSH-R; ULG5; hypergonadotropic hypogonadism; luteinizing hormone/choriogonadotropin receptor; lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor
Background
This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Glycoprotein hormone receptor
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
cAMPCHO-K1Human95-0106C2
β-ArrestinCHO-K1Human93-0957C2
 
Assay Readout ▲BackgroundSpeciesAssay Kit
cAMPCHO-K1Human95-0106E2CP2S
cAMPCHO-K1Human95-0106E2CP2M
cAMPCHO-K1Human95-0106E2CP2L
β-ArrestinCHO-K1Human93-0957E2CP0S
β-ArrestinCHO-K1Human93-0957E2CP0M
β-ArrestinCHO-K1Human93-0957E2CP0L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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