Find a Product

KISS1-derived peptide receptor (kisspeptin)

Target Class
GPCR
Family
Kisspeptin receptor
Official Symbol
KISS1R
Species
Human
Accession Number
NM_032551
Alias Names
AXOR12; G protein-coupled receptor 54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; GPR54; HOT7T175; KISS1 receptor; hypogonadotropin-1; kiSS-1 receptor; kiSS-1R; kisspeptins receptor; metastin receptor
Background
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty. [provided by RefSeq, Jul 2008]
+ Show More

Solution Portfolio

Related Family Members:

Kisspeptin receptor
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
β-ArrestinC2C12Human93-0504C7
β-ArrestinU2OSHuman93-0927C3
 
Assay Readout ▲BackgroundSpeciesAssay Kit
β-ArrestinU2OSHuman93-0927E3CP5S
β-ArrestinU2OSHuman93-0927E3CP5M
β-ArrestinU2OSHuman93-0927E3CP5L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms