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5-hydroxytryptamine receptor 1B (5HT1B)

Target Class
GPCR
Family
5-Hydroxytryptamine
Official Symbol
HTR1B
Species
Human
Accession Number
NM_000863
Alias Names
5-HT-1B; 5-HT-1D-beta; 5-HT1B; 5-HT1DB; 5-hydroxytryptamine (serotonin) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; 5-hydroxytryptamine receptor 1B; HTR1D2; HTR1DB; S12; serotonin 1D beta receptor; serotonin receptor 1B
Background
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM, Oct 2009]
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Solution Portfolio

Related Family Members:

5-Hydroxytryptamine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
cAMPCHO-K1Human 95-0162C2
β-ArrestinU2OSHuman93-0697C3
 
Assay Readout ▲BackgroundSpeciesAssay Kit
β-ArrestinU2OSHuman93-0697E3CP6S
β-ArrestinU2OSHuman93-0697E3CP6M
β-ArrestinU2OSHuman93-0697E3CP6L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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