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Histamine receptor H2 (H2)

Target Class
GPCR
Family
Histamine
Official Symbol
HRH2
Species
Human
Accession Number
AY136744
Alias Names
H2R; HH2R; gastric receptor 1; gastric receptor I; histamine H2 receptor; histamine receptor H2
Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
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Solution Portfolio

Related Family Members:

Histamine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0208C2
cAMP CHO-K1 Human 95-0043C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0043E2CP2S
cAMP CHO-K1 Human 95-0043E2CP2M
cAMP CHO-K1 Human 95-0043E2CP2L
β-Arrestin CHO-K1 Human 93-0208E2CP0S
β-Arrestin CHO-K1 Human 93-0208E2CP0M
β-Arrestin CHO-K1 Human 93-0208E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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