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Histamine receptor H1 (H1)

Target Class
GPCR
Family
Histamine
Official Symbol
HRH1
Species
Human
Accession Number
AY136743
Alias Names
H1-R; H1R; HH1R; hisH1; histamine H(1) receptor; histamine H1 receptor; histamine receptor H1; histamine receptor, subclass H1
Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Histamine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesAssay Kit
β-ArrestinCHO-K1Human93-0503E2CP2S
β-ArrestinCHO-K1Human93-0503E2CP2M
β-ArrestinCHO-K1Human93-0503E2CP2L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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