G-protein coupled receptor 84 (GPR84)
- Target Class
- GPCR
- Family
- Class A Orphan
- Official Symbol
- GPR84
- Species
- Human
- Accession Number
- NM_020370
- Alias Names
- EX33; G protein-coupled receptor 84; G-protein coupled receptor 84; GPCR4; inflammation-related G protein-coupled receptor EX33; inflammation-related G-protein coupled receptor EX33
- Background
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
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Solution Portfolio
Related Family Members:
Class A Orphan
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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