Find a Product

G-protein coupled receptor 84 (GPR84)

Target Class
GPCR
Family
Class A Orphan
Official Symbol
GPR84
Species
Human
Accession Number
NM_020370
Alias Names
EX33; G protein-coupled receptor 84; G-protein coupled receptor 84; GPCR4; inflammation-related G protein-coupled receptor EX33; inflammation-related G-protein coupled receptor EX33
Background
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
+ Show More

Solution Portfolio

Related Family Members:

Class A Orphan
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
cAMPCHO-K1Human95-0158C2
β-ArrestinCHO-K1Human93-0647C2
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms