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G-protein coupled receptor 39 (GPR39)

Target Class
GPCR
Family
Class A Orphan
Official Symbol
GPR39
Species
Human
Accession Number
NM_001508
Alias Names
G protein-coupled receptor 39; G-protein coupled receptor 39
Background
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
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Solution Portfolio

Related Family Members:

Class A Orphan
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0338C2
Calcium U2OS Human 95-1015C3
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0338E2CP1S
β-Arrestin CHO-K1 Human 93-0338E2CP1M
β-Arrestin CHO-K1 Human 93-0338E2CP1L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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