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G-protein coupled receptor 35 (GPR35)

Target Class
GPCR
Family
Class A Orphan
Official Symbol
GPR35
Species
Human
Accession Number
NM_005301
Alias Names
G protein-coupled receptor 35; G-protein coupled receptor 35; KYNA receptor; kynurenic acid receptor
Background
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
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Solution Portfolio

Related Family Members:

Class A Orphan
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0152C2
β-Arrestin CHO-K1 Human 93-0942C2
Internalization U2OS Human 93-0968C3
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0152E2CP2S
cAMP CHO-K1 Human 95-0152E2CP2M
cAMP CHO-K1 Human 95-0152E2CP2L
β-Arrestin CHO-K1 Human 93-0942E2CP2S
β-Arrestin CHO-K1 Human 93-0942E2CP2M
β-Arrestin CHO-K1 Human 93-0942E2CP2L
Internalization U2OS Human 93-0968E3CP5S
Internalization U2OS Human 93-0968E3CP5M
Internalization U2OS Human 93-0968E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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