G-protein coupled receptor 161 (GPR161)
- Target Class
- GPCR
- Family
- Class A Orphan
- Official Symbol
- GPR161
- Species
- Human
- Accession Number
- NM_153832.1
- Alias Names
- G protein-coupled receptor 161; G-protein coupled receptor 161; G-protein coupled receptor RE2; RE2
- Background
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008]
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Solution Portfolio
Related Family Members:
Class A Orphan
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0705C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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