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G-protein coupled receptor 161 (GPR161)

Target Class
GPCR
Family
Class A Orphan
Official Symbol
GPR161
Species
Human
Accession Number
NM_153832.1
Alias Names
G protein-coupled receptor 161; G-protein coupled receptor 161; G-protein coupled receptor RE2; RE2
Background
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008]
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Related Family Members:

Class A Orphan
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