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Gastric inhibitory polypeptide receptor (GIP)

Target Class
GPCR
Family
Glucagon
Official Symbol
GIPR
Species
Human
Accession Number
NM_000164
Alias Names
GIP-R; PGQTL2; gastric inhibitory polypeptide receptor; glucose-dependent insulinotropic polypeptide receptor
Background
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
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Solution Portfolio

Related Family Members:

Glucagon
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0146C2
β-Arrestin CHO-K1 Human 93-1095C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0788E2CP2S
β-Arrestin CHO-K1 Human 93-0788E2CP2M
β-Arrestin CHO-K1 Human 93-0788E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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