Formyl peptide receptor 3 (FPRL2)
- Target Class
- Official Symbol
- Accession Number
- Alias Names
- FML2_HUMAN; FMLP-R-II; FMLP-related receptor II; FMLPY; FPRH1; FPRH2; FPRL2; N-formyl peptide receptor 3; RMLP-R-I; formyl peptide receptor 3; formyl peptide receptor-like 2
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.+ Show More
Related Family Members:
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GPCR activation is often accompanied by the release of second messenger signaling molecules such as cAMP, Calcium, IP3 and cGMP, based on its G-protein binding partners. DiscoveRx offers a variety of cell lines and kits to study these second messenger signaling molecules as a measure of GPCR activity. Learn more about our Second Messengers.
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