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Free fatty acid receptor 3 (GPR41)

Target Class
Free Fatty Acid
Official Symbol
Accession Number
Alias Names
FFA3R; G protein-coupled receptor 41; G-protein coupled receptor 41; GPR41; free fatty acid receptor 3
Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5- trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.
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Solution Portfolio

Related Family Members:

Free Fatty Acid

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0136C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0136E2CP2L
cAMP CHO-K1 Human 95-0136E2CP2M
cAMP CHO-K1 Human 95-0136E2CP2S
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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Access your Target with Three Signaling Platforms