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Endothelin receptor type A (ETA)

Target Class
GPCR
Family
Endothelin
Official Symbol
EDNRA
Species
Human
Accession Number
AY275462
Alias Names
ET-A; ETA; ETA-R; ETAR; ETRA; G protein-coupled receptor; endothelin receptor subtype A; endothelin receptor type A; endothelin-1 receptor; endothelin-1-specific receptor; hET-AR
Background
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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Solution Portfolio

Related Family Members:

Endothelin
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesAssay Kit
β-ArrestinCHO-K1Human93-0257E2CP0S
β-ArrestinCHO-K1Human93-0257E2CP0M
β-ArrestinCHO-K1Human93-0257E2CP0L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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