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Endothelin receptor type A (ETA)

Target Class
GPCR
Family
Endothelin
Official Symbol
EDNRA
Species
Human
Accession Number
AY275462
Alias Names
ET-A; ETA; ETA-R; ETAR; ETRA; G protein-coupled receptor; endothelin receptor subtype A; endothelin receptor type A; endothelin-1 receptor; endothelin-1-specific receptor; hET-AR
Background
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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Solution Portfolio

Related Family Members:

Endothelin
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0257C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0257E2CP0S
β-Arrestin CHO-K1 Human 93-0257E2CP0M
β-Arrestin CHO-K1 Human 93-0257E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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