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Sphingosine 1-phosphate receptor 4 (S1P4)

Target Class
GPCR
Family
Lysophospholipid (S1P)
Official Symbol
EDG6
Species
Human
Accession Number
AY322537
Alias Names
S1PR4; EDG6; LPC1; S1P receptor 4; S1P receptor Edg-6; S1P4; SLP4; endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, G protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; sphingosine 1-phosphate receptor 4; sphingosine 1-phosphate receptor Edg-6; sphingosine-1-phosphate receptor 4
Background
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Lysophospholipid (S1P)
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Arrestin Assays
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DiscoveRx PathHunter ß-Arrestin GPCR assays are a cell-based functional assay that quantitatively measures GPCR activation through ß-Arrestin recruitment to activated GPCRs. This offers a simple, yet powerful screening and profiling platform that can be used for almost all Gi-, Gs-, or Gq-coupled receptor. Learn more about our Arrestin Assays.

Assay Readout Background Cell Lines
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DiscoveRx offers stable and validated cell lines of unsurpassed quality and leading performance, engineered using our proprietary EFC technology. These engineered cell lines form the basis of our cell-based assays for a broad range of target classes in a variety of cell backgrounds, ideal for screening and profiling both small molecules and biologics. Learn more about our Cell Lines.

Assay Ready Kits
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DiscoveRx Assay Ready kits are ready-to-ship, ready-to-use kits that contain all the necessary reagents to perform a functional whole-cell assay including frozen pre-validated cells, detection reagents, media and plates, with a simple thaw-plate-read protocol. DiscoveRx offers a variety of Assay Ready kits. Learn more about our Assay Ready Kits.

Orthologs Services
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DiscoveRx offers a variety of service options designed to support you at every stage of drug development. We offer screening and profiling services for small molecules and biologics, using DiscoveRx cell lines anchored in the EFC and competition binding technology platforms. We can develop custom assay solutions tailored to meet your needs and provide scale up options for our cell lines and supporting components. Learn more about DiscoveRx Services.

β-Arrestin-2 CHO-K1 93-0227C2 (β-Arrestin/Ca2+) mouse
Yes
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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