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Lysophosphatidic acid receptor 2 (LPA2)

Target Class
GPCR
Family
Lysophospholipid (LPA)
Official Symbol
EDG4
Species
Human
Accession Number
AY322548
Alias Names
LPAR2; EDG-4; EDG4; G protein-coupled receptor; LPA receptor 2; LPA receptor EDG4; LPA-2; LPA2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; lysophosphatidic acid receptor 2; lysophosphatidic acid receptor EDG4; lysophosphatidic acid receptor Edg-4
Background
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Lysophospholipid (LPA)
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0255C2
Calcium CHO-K1 Human 95-1012C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0255E2CP13S
β-Arrestin CHO-K1 Human 93-0255E2CP13M
β-Arrestin CHO-K1 Human 93-0255E2CP13L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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