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Sphingosine 1-phosphate receptor 1 (S1P1)

Target Class
GPCR
Family
Lysophospholipid (S1P)
Official Symbol
EDG1
Species
Human
Accession Number
NM_001400
Alias Names
S1PR1; CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P receptor 1; S1P receptor Edg-1; S1P1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1
Background
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Lysophospholipid (S1P)
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0207C2
Internalization HEK 293 Human 93-0784C1
cAMP CHO-K1 Human 95-0142C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0207E2CP4S
β-Arrestin CHO-K1 Human 93-0207E2CP4M
β-Arrestin CHO-K1 Human 93-0207E2CP4L
Internalization HEK 293 Human 93-0784E1CP28S
Internalization HEK 293 Human 93-0784E1CP28M
Internalization HEK 293 Human 93-0784E1CP28L
cAMP CHO-K1 Human 95-0142E2CP20L
cAMP CHO-K1 Human 95-0142E2CP20M
cAMP CHO-K1 Human 95-0142E2CP20S
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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