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Dopamine Receptor D3 (D3)

Target Class
GPCR
Family
Dopamine
Official Symbol
DRD3
Species
Human
Accession Number
NM_000796.3
Alias Names
D(3) dopamine receptor; D3DR; ETM1; FET1; dopamine D3 receptor; dopamine receptor D3; essential tremor 1
Background
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Dopamine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0591C2
β-Arrestin U2OS Human 93-0591C3
Assay Readout Background Species Assay Kit
β-Arrestin U2OS Human 93-0591E3CP0S
β-Arrestin U2OS Human 93-0591E3CP0M
β-Arrestin U2OS Human 93-0591E3CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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