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Dopamine Receptor D2 (short isoform) (D2S)

Target Class
GPCR
Family
Dopamine
Official Symbol
DRD2S
Species
Human
Accession Number
NM_016574.3
Alias Names
D(2) dopamine receptor; D2DR; D2R; dopamine D2 receptor; dopamine receptor D2; dopamine receptor D2 isoform; seven transmembrane helix receptor
Background
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Dopamine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0351C2
cAMP CHO-K1 Human 95-0084C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0084E2CP2S
cAMP CHO-K1 Human 95-0084E2CP2M
cAMP CHO-K1 Human 95-0084E2CP2L
β-Arrestin CHO-K1 Human 93-0351E2CP0S
β-Arrestin CHO-K1 Human 93-0351E2CP0M
β-Arrestin CHO-K1 Human 93-0351E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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