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Dopamine receptor D1 (D1)

Target Class
GPCR
Family
Dopamine
Official Symbol
DRD1
Species
Human
Accession Number
NM_000794.3
Alias Names
D(1A) dopamine receptor; DADR; DRD1A; dopamine D1 receptor; dopamine receptor D1
Background
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Dopamine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0590C2
Internalization U2OS Human 93-0748C3
cAMP CHO-K1 Human 95-0083C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0083E2CP2S
cAMP CHO-K1 Human 95-0083E2CP2M
cAMP CHO-K1 Human 95-0083E2CP2L
β-Arrestin CHO-K1 Human 93-0590E2CP2S
β-Arrestin CHO-K1 Human 93-0590E2CP2M
β-Arrestin CHO-K1 Human 93-0590E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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