Dopamine receptor D1 (D1)
- Target Class
- GPCR
- Family
- Dopamine
- Official Symbol
- DRD1
- Species
- Human
- Accession Number
- NM_000794.3
- Alias Names
- D(1A) dopamine receptor; DADR; DRD1A; dopamine D1 receptor; dopamine receptor D1
- Background
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Dopamine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
β-Arrestin |
CHO-K1 |
Human |
93-0590C2 |
Internalization |
U2OS |
Human |
93-0748C3 |
cAMP |
CHO-K1 |
Human |
95-0083C2 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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