Duffy blood group, chemokine receptor (FY)
- Target Class
- GPCR
- Family
- Chemokine
- Official Symbol
- DARC
- Species
- Human
- Accession Number
- NM_002036.2
- Alias Names
- CCBP1; CD234; Dfy; Duffy antigen/chemokine receptor; Duffy blood group; Duffy blood group antigen; Duffy blood group, chemokine receptor; FY; Fy glycoprotein; GPD; GpFy; WBCQ1; glycoprotein D; plasmodium vivax receptor
- Background
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Chemokine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
β-Arrestin |
CHO-K1 |
Human |
93-0548C2 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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