Duffy blood group, chemokine receptor (FY)

Target Class
GPCR
Family
Chemokine
Official Symbol
DARC
Species
Human
Accession Number
NM_002036.2
Alias Names
CCBP1; CD234; Dfy; Duffy antigen/chemokine receptor; Duffy blood group; Duffy blood group antigen; Duffy blood group, chemokine receptor; FY; Fy glycoprotein; GPD; GpFy; WBCQ1; glycoprotein D; plasmodium vivax receptor
Background
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Chemokine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0548C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0548E2CP1M
β-Arrestin CHO-K1 Human 93-0548E2CP1L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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