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Chemokine (C-C motif) receptor 6 (CCR6)

Target Class
GPCR
Family
Chemokine
Official Symbol
CCR6
Species
Human
Accession Number
AY242126
Alias Names
BN-1; C-C CKR-6; C-C chemokine receptor type 6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; G protein-coupled receptor 29; G-protein coupled receptor 29; GPR29; GPRCY4; LARC receptor; STRL22; chemokine (C-C motif) receptor 6; chemokine (C-C) receptor 6; chemokine receptor-like 3; seven-transmembrane receptor, lymphocyte, 22
Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Chemokine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0194C2
cAMP CHO-K1 Human 95-0069C2
Internalization U2OS Human 93-0966C3
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0069E2CP2S
cAMP CHO-K1 Human 95-0069E2CP2M
cAMP CHO-K1 Human 95-0069E2CP2L
β-Arrestin CHO-K1 Human 93-0194E2CP0S
β-Arrestin CHO-K1 Human 93-0194E2CP0M
β-Arrestin CHO-K1 Human 93-0194E2CP0L
Internalization U2OS Human 93-0966E3CP5S
Internalization U2OS Human 93-0966E3CP5M
Internalization U2OS Human 93-0966E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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