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Chemokine (C-C motif) receptor 4 (CCR4)

Target Class
GPCR
Family
Chemokine
Official Symbol
CCR4
Species
Human
Accession Number
AY322539
Alias Names
C-C CKR-4; C-C chemokine receptor type 4; CC-CKR-4; CCR-4; CD194; CKR4; CMKBR4; ChemR13; HGCN:14099; K5-5; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4
Background
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Chemokine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0193C2
Internalization U2OS Human 93-0845C3
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0193E2CP0S
β-Arrestin CHO-K1 Human 93-0193E2CP0M
β-Arrestin CHO-K1 Human 93-0193E2CP0L
Internalization U2OS Human 93-0845E3CP27S
Internalization U2OS Human 93-0845E3CP27M
Internalization U2OS Human 93-0845E3CP27L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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