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Calcitonin receptor (CT)

Target Class
GPCR
Family
Calcitonin
Official Symbol
CALCR-RAMP3
Species
Human
Accession Number
NM_001742.2
Alias Names
CRLR activity-modifying protein 3; calcitonin receptor-like receptor activity modifying protein 3; calcitonin-receptor-like receptor activity-modifying protein 3; receptor (G protein-coupled) activity modifying protein 3; receptor (calcitonin) activity modifying protein 3; receptor activity modifying protein 3; receptor activity-modifying protein 3; receptor-activity-modifying protein 3
Background
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Calcitonin
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
cAMP 1321N1 Human 95-0166C6
β-Arrestin CHO-K1 Human 93-0268C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0268E2CP0S
β-Arrestin CHO-K1 Human 93-0268E2CP0M
β-Arrestin CHO-K1 Human 93-0268E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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