Calcitonin receptor (CT)
- Target Class
- GPCR
- Family
- Calcitonin
- Official Symbol
- CALCR
- Species
- Human
- Accession Number
- NM_001742.2
- Alias Names
- CRT; CT-R; CTR; CTR1; calcitonin receptor
- Background
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
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Solution Portfolio
Related Family Members:
Calcitonin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
β-Arrestin |
CHO-K1 |
Human |
93-0566C2 |
β-Arrestin |
U2OS |
Human |
93-0566C3 |
cAMP |
CHO-K1 |
Human |
95-0161C2 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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