Adrenergic receptor alpha 1A (α1A-adrenoceptor)
- Target Class
- GPCR
- Family
- Adrenoceptors
- Official Symbol
- ADRA1A
- Species
- Human
- Accession Number
- NM_000680
- Alias Names
- ADRA1C; ADRA1L1; ALPHA1AAR; G protein coupled receptor; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1A-, receptor variant 1; adrenergic, alpha-1A-, receptor variant 3; adrenergic, alpha-1A-, receptor variant 5; adrenergic, alpha-1A-, receptor variant 8; alpha-1A adrenergic receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor; a1A
- Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Adrenoceptors
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| Calcium |
CHO-K1 |
Human |
95-1023C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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