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Adrenergic receptor alpha 1A (α1A-adrenoceptor)

Target Class
GPCR
Family
Adrenoceptors
Official Symbol
ADRA1A
Species
Human
Accession Number
NM_000680
Alias Names
ADRA1C; ADRA1L1; ALPHA1AAR; G protein coupled receptor; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1A-, receptor variant 1; adrenergic, alpha-1A-, receptor variant 3; adrenergic, alpha-1A-, receptor variant 5; adrenergic, alpha-1A-, receptor variant 8; alpha-1A adrenergic receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor; a1A
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Adrenoceptors
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
Calcium CHO-K1 Human 95-1023C2
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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